Researchers may have found noninvasive test for identifying lymph node metastasis
Jan 13, 2012
In recent breast cancer breakthroughs news, researchers are suggesting that there may be a new, noninvasive way to identify lymph node metastases.
A study out of the Moffitt Cancer Center has been developing fluorescent molecular imaging probes that could be non-invasivewhen testing for breast cancer. The scientists are hopeful that this could help in the prognosis of millions of women being tested.
"The majority of breast cancer patients, up to 74 percent, who undergo SLN biopsy are found to be negative for axillary nodal, or ALN, metastases," said corresponding author Dr. David L. Morse, an associate member at Moffitt. "Determining the presence or absence of ALN metastasis is critical to breast cancer staging and prognosis. Because of the unreliability of the SLN biopsy and its potential for adverse effects, a noninvasive, more accurate method to assess lymph node involvement is needed."
However, the researchers noted that there is still work to be done before the system is perfected. Biopsies failed to identify the disease in axillary lymph nodes in between 5 to 10 percent of patients.